CutDB: a proteolytic event database
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  • Number of proteolytic events found : 128
  • Display mode: Flexibility of connection: Steps of expanding:
  • Events created with ID=24702 or lower, will be used in reconstruction.
  • ID Protease Organism [protease] Substrate Organism [substrate] Cut-site Structure Update Detail
    calpain-1C02.001 Homo sapiens SPTBN1
    spectrin, beta, non-erythrocytic 1 isoform 2
    Homo sapiens EKSA-ATWD
    2053-2054
    Dec 19
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens CASP14
    Caspase 14 precursor
    Homo sapiens VMVI-KDSP
    152-153
    Detail
    calpain-1C02.001 Homo sapiens CDK5R1
    Cyclin-dependent kinase 5, regulatory subunit 1
    Homo sapiens LSTF-AQPP
    98-99
    Detail
    calpain-1C02.001 Homo sapiens TP53
    Tumor protein p53
    Homo sapiens SQET-FSDL
    18-19
    Detail
    calpain-1C02.001 Homo sapiens TP53
    Tumor protein p53
    Homo sapiens ETFS-DLWK
    20-21
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    Integrin beta chain, beta 3 precursor
    Homo sapiens NITY-RGT
    785-786
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    Integrin beta chain, beta 3 precursor
    Homo sapiens TSTF-TNIT
    780-781
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    Integrin beta chain, beta 3 precursor
    Homo sapiens NPLY-KEAT
    773-774
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    Integrin beta chain, beta 3 precursor
    Homo sapiens KWDT-ANNP
    767-768
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    Integrin beta chain, beta 3 precursor
    Homo sapiens EERA-RAKW
    761-762
    Detail
    calpain-1C02.001 Homo sapiens BID
    Bh3 interacting domain death agonist isoform 2
    Homo sapiens WEGY-DELQ
    54-55
    Detail
    calpain-1C02.001 Homo sapiens BCL2L1
    Bcl2-like 1 isoform 1
    Homo sapiens EGTE-SEME
    42-43
    Detail
    calpain-1C02.001 Homo sapiens SPTAN1
    Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
    Homo sapiens QEVY-GMMP
    1176-1177
    Dec 22
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens SPTBN1
    spectrin, beta, non-erythrocytic 1 isoform 1
    Homo sapiens EKSA-ATWD
    2066-2067
    Dec 19
    2006
    YI
    Detail
    calpain-1
    somatostatin preproprotein
    Homo sapiens FWKT-FTSC
    112-113
    Mar 12
    2007
    Detail
    calpain-1C02.001 Homo sapiens NTS
    neurotensin/neuromedin N preproprotein
    Homo sapiens RQLY-ENKP
    153-154
    Nov 14
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens CAPN1
    calpain 1, large subunit
    Homo sapiens TGVS-AQVQ
    15-16
    May 10
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens CAPN1
    calpain 1, large subunit
    Homo sapiens RELG-LGRH
    27-28
    May 10
    2007
    YI
    Detail
    calpain-1 luteinizing hormone releasing hormone Detail
    calpain-1C02.001 Homo sapiens ITGB3
    integrin beta chain, beta 3 precursor
    Homo sapiens NITY-RGT-
    785-786
    Jan 18
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    integrin beta chain, beta 3 precursor
    Homo sapiens NPLY-KEAT
    773-774
    Jan 18
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    integrin beta chain, beta 3 precursor
    Homo sapiens KWDT-ANNP
    767-768
    Jan 18
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    integrin beta chain, beta 3 precursor
    Homo sapiens TSTF-TNIT
    780-781
    Jan 18
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens ITGB3
    integrin beta chain, beta 3 precursor
    Homo sapiens EERA-RAKW
    761-762
    Jan 18
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens BAX
    BCL2-associated X protein isoform alpha
    Homo sapiens FIQD-RAGR
    33-34
    Jan 10
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens SPTAN1
    spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
    Homo sapiens QEVY-GMMP
    1176-1177
    Jan 10
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens CDK5R1
    cyclin-dependent kinase 5, regulatory subunit 1
    Homo sapiens LSTF-AQPP
    98-99
    Jan 09
    2007
    YI
    Detail
    calpain-1C02.001 Mus musculus Prnp
    prion protein
    Mus musculus GGGW-GQGG
    88-89
    Feb 02
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens LIG3
    ligase III, DNA, ATP-dependent isoform beta precursor
    Homo sapiens Dec 21
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens ZAP70
    zeta-chain associated protein kinase 70kDa isoform 1
    Homo sapiens Dec 21
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens CDH1
    cadherin 1, type 1 preproprotein
    Homo sapiens Dec 22
    2006
    YI
    Detail
    calpainC02.001 Homo sapiens
    connexin-32
    Mus musculus Dec 25
    2006
    AndreiO
    Detail
    calpain-1C02.001 Homo sapiens PTPN4
    protein tyrosine phosphatase, non-receptor type 4
    Homo sapiens Dec 28
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens PICALM
    phosphatidylinositol-binding clathrin assembly protein isoform 1
    Homo sapiens Dec 28
    2006
    YI
    Detail
    calpain-1C02.001 Homo sapiens PTPN6
    protein tyrosine phosphatase, non-receptor type 6 isoform 1
    Homo sapiens Feb 13
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens PTPN6
    protein tyrosine phosphatase, non-receptor type 6 isoform 2
    Homo sapiens Feb 13
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens CDK5R1
    cyclin-dependent kinase 5, regulatory subunit 1
    Homo sapiens LSTF-AQPP
    98-99
    Jul 30
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens Gjb1
    gap junction membrane channel protein beta 1
    Mus musculus Jan 30
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens BID
    Bh3 interacting domain death agonist isoform 2
    Homo sapiens SRLG-RIEA
    70-71
    Jan 08
    2007
    YI
    Detail
    calpain-1C02.001 Mus musculus Abca1
    ATP-binding cassette 1, sub-family A, member 1
    Mus musculus Jan 09
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens IL1A
    interleukin 1, alpha proprotein
    Homo sapiens Jan 12
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens PTPN1
    protein tyrosine phosphatase, non-receptor type 1
    Homo sapiens Jan 30
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens CAMK4
    calcium/calmodulin-dependent protein kinase IV
    Homo sapiens EN-LVPD
    27-28
    Jan 15
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens CAMK4
    calcium/calmodulin-dependent protein kinase IV
    Homo sapiens TVCG-TPGY
    203-204
    Jan 15
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens POLE
    DNA polymerase epsilon catalytic subunit
    Homo sapiens Jan 15
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens ADD3
    adducin 3 (gamma) isoform a
    Homo sapiens Jan 16
    2007
    YI
    Detail
    calpain-1C02.001 Sus scrofa SNAP23
    synaptosomal-associated protein 23 isoform SNAP23A
    Homo sapiens Jan 16
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens TNNI3
    troponin I, cardiac
    Homo sapiens Jan 17
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens TP73
    tumor protein p73
    Homo sapiens Jan 29
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens UTRN
    utrophin
    Homo sapiens Mar 05
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens STAT3
    signal transducer and activator of transcription 3 isoform 1
    Homo sapiens Feb 28
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens STAT5B
    signal transducer and activator of transcription 5B
    Homo sapiens Feb 28
    2007
    YI
    Detail
    calpain-1C02.001 Homo sapiens HTT
    huntingtin
    Homo sapiens SALT-ASVK
    469-470
    Apr 16
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens HTT
    huntingtin
    Homo sapiens SHSS-SQVS
    536-537
    Apr 16
    2008
    Alex
    Detail
    calpain-1C02.001 Mus musculus Des
    desmin
    Mus musculus Apr 21
    2008
    Alex
    Detail
    calpain-1C02.001 Mus musculus Prkca
    protein kinase C, alpha
    Mus musculus Apr 21
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens CAST
    calpastatin isoform a
    Homo sapiens May 02
    2008
    Isola
    Detail
    calpain-1C02.001 Homo sapiens SNCA
    alpha-synuclein isoform NACP140
    Homo sapiens KGLS-KAKE
    9-10
    Jul 28
    2008
    YI
    Detail
    calpain-1C02.001 Homo sapiens SNCA
    alpha-synuclein isoform NACP140
    Homo sapiens DPDN-EAYE
    122-123
    May 05
    2008
    Isola
    Detail
    calpain-1C02.001 Bos taurus Ank1
    ankyrin 1, erythroid
    Rattus norvegicus Jun 11
    2008
    Alex
    Detail
    calpain-1C02.001 Bos taurus Ank2
    ankyrin 2 isoform 2
    Rattus norvegicus Jun 11
    2008
    Alex
    Detail
    calpain-1C02.001 Bos taurus Ank2
    ankyrin 2 isoform 1
    Rattus norvegicus Jun 11
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens calponin alpha
    calponin alpha
    Gallus gallus Jun 12
    2008
    Alex
    Detail
    calpain Homo sapiens DRP2
    dystrophin related protein 2
    Homo sapiens Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens PTPRN
    protein tyrosine phosphatase, receptor type, N precursor
    Homo sapiens RQQD-KERL
    608-609
    Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens PTPRN
    protein tyrosine phosphatase, receptor type, N precursor
    Homo sapiens SVSS-QFSD
    659-660
    Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Mus musculus Neb
    nebulin
    Mus musculus Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Mus musculus Dmd
    dystrophin, muscular dystrophy
    Mus musculus Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Mus musculus Vcl
    vinculin
    Mus musculus Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens KNG1
    kininogen 1
    Homo sapiens Jun 12
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens MAPT
    microtubule-associated protein tau isoform 6
    Homo sapiens Jul 28
    2008
    Alex
    Detail
    calpain-1C02.001 Rattus norvegicus similar to titin isoform N2-A Rattus norvegicus Jun 14
    2008
    Alex
    Detail
    calpain-1C02.001 Rattus norvegicus Ttn
    similar to titin isoform N2-B
    Rattus norvegicus Jun 14
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens VMAC
    vimentin
    Homo sapiens Jun 14
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens TUBB
    tubulin, beta
    Homo sapiens Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens ENO1
    enolase 1
    Homo sapiens Jun 14
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens HSPA8
    heat shock 70kDa protein 8 isoform 1
    Homo sapiens Jun 14
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 1
    Homo sapiens LILQ-LCIG
    298-299
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 1
    Homo sapiens RVNK-LILQ
    294-295
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 2
    Homo sapiens RVNK-LILQ
    294-295
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 2
    Homo sapiens LILQ-LCIG
    298-299
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 5
    Homo sapiens RVNK-LILQ
    252-253
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 5
    Homo sapiens LILQ-LCIG
    256-257
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 6
    Homo sapiens RVNK-LILQ
    252-253
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 6
    Homo sapiens LILQ-LCIG
    257-258
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 7
    Homo sapiens RVNK-LILQ
    211-212
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens NF2
    neurofibromin 2 isoform 7
    Homo sapiens LILQ-LCIG
    215-216
    Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens lamin Astropecten pectinifera Jun 15
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens growth associated protein 43 Bos taurus Jun 17
    2008
    Alex
    Detail
    calpain-1C02.001 Rattus norvegicus Grin2b
    glutamate receptor, ionotropic, N-methyl D-aspartate 2B
    Rattus norvegicus Jun 17
    2008
    Alex
    Detail
    calpain-1C02.001 Rattus norvegicus Grin2a
    glutamate receptor, ionotropic, N-methyl D-aspartate 2A
    Rattus norvegicus Jun 17
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens PPP3CA
    protein phosphatase 3, catalytic subunit, alpha isoform
    Homo sapiens SINK-ALTS
    501-502
    Jul 28
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens SLC6A3
    solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
    Homo sapiens VQLT-SSTL
    43-44
    Jun 17
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens SLC6A3
    solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
    Homo sapiens DFLL-SVIG
    71-72
    Jun 17
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens RB1
    retinoblastoma 1
    Homo sapiens SPLK-SPYK
    810-811
    Jun 18
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens RHOA
    ras homolog gene family, member A
    Homo sapiens AALQ-ARRG
    180-181
    Jul 19
    2009
    SG
    Detail
    calpain-1C02.001 Mus musculus Pxn
    paxillin isoform beta
    Mus musculus Aug 20
    2008
    Alex
    Detail
    calpain-1C02.001 Mus musculus Pxn
    paxillin isoform alpha
    Mus musculus Aug 20
    2008
    Alex
    Detail
    calpain-1C02.001 Homo sapiens AMPH
    amphiphysin isoform 1
    Homo sapiens PEIS-VTTP
    333-334
    Nov 06
    2008
    SG
    Detail
    calpain-1C02.001 Homo sapiens AMPH
    amphiphysin isoform 1
    Homo sapiens SPMS-QTLP
    377-378
    Nov 06
    2008
    SG
    Detail
    calpain-1C02.001 Homo sapiens AMPH
    amphiphysin isoform 1
    Homo sapiens TDLV-QPAS
    392-393
    Nov 06
    2008
    SG
    Detail
    calpain-1C02.001 Homo sapiens PICALM
    phosphatidylinositol-binding clathrin assembly protein isoform 2
    Homo sapiens Jan 27
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens F2R
    coagulation factor II receptor precursor
    Homo sapiens PESK-ATNA
    32-33
    Jun 15
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens F2R
    coagulation factor II receptor precursor
    Homo sapiens SINK-SSPL
    76-77
    Jun 15
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens F2RL1
    coagulation factor II (thrombin) receptor-like 1 precursor
    Homo sapiens ETVF-SVDE
    59-60
    Jun 15
    2009
    SG
    Detail
    calpain-1C02.001 Rattus norvegicus Prkca
    protein kinase C, alpha
    Rattus norvegicus AGNK-VISP
    316-317
    Jun 20
    2009
    SG
    Detail
    calpain-1C02.001 Rattus norvegicus Prkca
    protein kinase C, alpha
    Rattus norvegicus SEDR-KQPS
    324-325
    Jun 20
    2009
    SG
    Detail
    calpain-1C02.001 Rattus norvegicus Prkcb
    protein kinase C, beta
    Rattus norvegicus AKIG-QGTK
    311-312
    Jun 20
    2009
    SG
    Detail
    calpain-1C02.001 Rattus norvegicus Prkcb
    protein kinase C, beta
    Rattus norvegicus PEEK-TANT
    320-321
    Jun 20
    2009
    SG
    Detail
    calpain-1C02.001 Rattus norvegicus Prkcg
    protein kinase C, gamma
    Rattus norvegicus GPSS-SPIP
    321-322
    Jun 20
    2009
    SG
    Detail
    calpain-1C02.001 Rattus norvegicus Prkcg
    protein kinase C, gamma
    Rattus norvegicus KRCF-FGAS
    338-339
    Jun 20
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa Grin2a
    glutamate receptor, ionotropic, N-methyl D-aspartate 2A
    Rattus norvegicus NALQ-FQKN
    1278-1279
    Jul 01
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa Grin2a
    glutamate receptor, ionotropic, N-methyl D-aspartate 2A
    Rattus norvegicus GSLF-SVPS
    1329-1330
    Jul 01
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa Grin2c
    glutamate receptor, ionotropic, N-methyl D-aspartate 2C
    Rattus norvegicus Jul 01
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa CASP9
    caspase 9 isoform alpha preproprotein
    Homo sapiens RPEI-RKPE
    115-116
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa CASP9
    caspase 9 isoform beta preproprotein
    Homo sapiens RPEI-RKPE
    115-116
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa CASP9
    caspase 9 isoform alpha preproprotein
    Homo sapiens KPEV-LRPE
    120-121
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa CASP9
    caspase 9 isoform beta preproprotein
    Homo sapiens KPEV-LRPE
    120-121
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa CASP9
    caspase 9 isoform alpha preproprotein
    Homo sapiens GALE-SLRG
    143-144
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Sus scrofa CASP3
    caspase 3 preproprotein
    Homo sapiens TENS-VDSK
    7-8
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens ATP2B2
    plasma membrane calcium ATPase 2 isoform 1
    Homo sapiens RELR-RGQI
    1124-1125
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens ATP2B2
    plasma membrane calcium ATPase 2 isoform 1
    Homo sapiens RGLN-RIQT
    1135-1136
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens ATP2B2
    plasma membrane calcium ATPase 2 isoform 2
    Homo sapiens RELR-RGQI
    1079-1080
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens ATP2B2
    plasma membrane calcium ATPase 2 isoform 2
    Homo sapiens RGLN-RIQT
    1090-1091
    Jul 02
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens STAT5A
    signal transducer and activator of transcription 5A
    Homo sapiens Jul 03
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens PTK2
    PTK2 protein tyrosine kinase 2 isoform a
    Homo sapiens Jul 03
    2009
    SG
    Detail
    calpain-1C02.001 Homo sapiens PTK2
    PTK2 protein tyrosine kinase 2 isoform b
    Homo sapiens Jul 03
    2009
    SG
    Detail
    calpain-1 Oryctolagus cuniculus MAP2
    microtubule-associated protein 2 isoform 1
    Bos taurus Aug 03
    2009
    SG
    Detail