CutDB: a proteolytic event database
  • User: anonymous [ Log in ]

    • Substrate
    Definition: cortactin isoform a
    Symbol: CTTN
    Organism: Homo sapiens
    NCBI Accession: NP_005222
    SubstrateDB: 18044
    [Sequence on/off]
    MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLK
    EKELETGPKASHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE
    YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSA
    VGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQ
    DSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSNI
    RANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKTQTPPVSPAPQPTEERLPSSPV
    YEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYDEYE
    NDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: AYQK-TVPV
    Position: 336-337
    Protease
    Definition: calpain-2
    Organism: Homo sapiens
    MEROPS ID: MER000964
    PMAP ID: pmap.22797
    MEROPS code: C02.002
    Consequence
    Inactivation_complete
    Co-factor
    Calcium
    Pathway
    Cell Migration
    Cell_compartment
    Cytosol;
    Tissue
    fibroblast
    Method_of_ID
    Others
    Original citation
    Comments and others