CutDB: a proteolytic event database
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  • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: secreted protein, acidic, cysteine-rich (osteonectin)
    Symbol: SPARC
    Organism: Homo sapiens
    NCBI Accession: NP_003109
    SubstrateDB: 19288
    UniProt Accession: P09486
    [Sequence on/off]
    MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEEVVAEN
    PCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHK
    LHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGD
    HPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKY
    IALDEWAGCFGIKQKDIDKDLVI
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: CPAP-IGEF
    Position: 104-105
    Protease
    Definition: matrix metallopeptidase-3
    Organism: Homo sapiens
    MEROPS ID: MER001068
    PMAP ID: pmap.41854
    MEROPS code: M10.005
    Consequence
    Others
    Disease
    Fibrosis
    Method_of_ID
    N-terminal sequencing
    Original citation
    Comments and others