CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: caspase 8 isoform C precursor
    Symbol: CASP8
    Organism: Homo sapiens
    NCBI Accession: 122056474
    SubstrateDB: 22087
    UniProt Accession: Q14790
    [Sequence on/off]
    MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRIN
    RLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLL
    DIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKGEELCGVMTISDSPREQDSESQTLDKV
    YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEI
    LKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNY
    QKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPR
    GDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: PKVF-FIQA
    Position: 340-341
    Protease
    Definition: HIV-1 retropepsin
    Organism: Human immunodeficiency virus
    MEROPS ID: MER056744
    PMAP ID: pmap.08187
    MEROPS code: A02.001
    Consequence
    Others
    Disease
    AIDS
    Method_of_ID
    Mass spectrometry
    Original citation
    Comments and others