CutDB: a proteolytic event database
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    • Substrate
    Definition: sodium channel, nonvoltage-gated 1 gamma
    Symbol: Scnn1g
    Organism: Mus musculus
    NCBI Accession: NP_035456
    SubstrateDB: 23009
    [Sequence on/off]
    MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCLNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQ
    CALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPR
    KRREAGSMRSTWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGF
    QLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTL
    FHHPMYGNCYTFNNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVG
    TEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQ
    PLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVL
    TWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFF
    IDFFSIIARRQWQKAKDWWARRRTPPSTETPSSQQGQDNPALDTDDDLPTFTSAMRLPPAPEAPVPGTPP
    PRYNTLRLDSAFSSQLTDTQLTNEF
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: RKRK-ISGK
    Position: 186-187
    Protease
    Definition: prostasin
    Organism: Mus musculus
    MEROPS ID: MER013866
    PMAP ID: pmap.39197
    MEROPS code: S01.159
    Consequence
    Activation_complete
    Pathway
    channel activation
    Method_of_ID
    Mutagenesis
    Original citation
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