CutDB: a proteolytic event database
  • User: anonymous [ Log in ]

    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: sodium channel, nonvoltage-gated, type I, alpha
    Symbol: Scnn1a
    Organism: Rattus norvegicus
    NCBI Accession: NP_113736
    SubstrateDB: 26759
    [Sequence on/off]
    MMLDHTRAPELNIDLDLHASNSPKGSMKGNQFKEQDPCPPQPMQGLGKGDKREEQGLGPEPSAPRQPTEE
    EEALIEFHRSYRELFQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYLSYPV
    SLNINLNSDKLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGARRRSSRDLLG
    AFPHPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSGVDAVREWY
    RFHYINILSRLSDTSPALEEEALGNFIFTCRFNQAPCNQANYSKFHHPMYGNCYTFNDKNNSNLWMSSMP
    GVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISMRKEALDSLGGNYG
    DCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYPKPKGVEFCDYRKQSSWGYCYYKLQG
    AFSLDSLGCFSKCRKPCSVINYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELN
    YKTNSESPSVTMVSLLSNLGSQWSLWFGSSVLSVVEMAELIFDLLVITLLMLLRRFRSRYWSPGRGARGA
    REVASTPASSFPSRFCPHPTSPPPSLPQQGMTPPLALTAPPPAYATLGPSAPPLDSAAPDCSACALAAL
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: RSSR-DLLG
    Position: 206-207
    Protease
    Definition: transmembrane peptidase, serine 4
    Organism: Rattus norvegicus
    MEROPS ID: MER056211
    PMAP ID: pmap.03644
    MEROPS code: S01.034
    Consequence
    Activation_complete
    Disease
    Hypertension
    Method_of_ID
    Mutagenesis
    Original citation
    Comments and others