CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: sodium channel, nonvoltage-gated 1 beta
    Symbol: Scnn1b
    Organism: Rattus norvegicus
    NCBI Accession: NP_036780
    SubstrateDB: 26762
    [Sequence on/off]
    MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVF
    IQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKILAPKSSHTNTTSTL
    NFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTSAT
    QAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEK
    ALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLLDKLQ
    GKGEPYSPCTMNGSDVAIQNLYSDYNTTYSIQACLHSCFQDHMIHNCSCGHYLYPLPAGEKYCNNRDFPD
    WAYCYLSLQMSVVQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGI
    VKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITVIKLVASCKGL
    RRRRPQRPYTGPPPTVAELVEAHTNCVFQPDTTSCRPNAEVYPDQQTLPIPGTPPPNYDSLRLQPLDTME
    SDSEVEAI
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: FNYR-TIEE
    Position: 503-504
    Protease
    Definition: transmembrane peptidase, serine 4
    Organism: Rattus norvegicus
    MEROPS ID: MER056211
    PMAP ID: pmap.03644
    MEROPS code: S01.034
    Consequence
    Activation_complete
    Disease
    Hypertension
    Method_of_ID
    Mutagenesis
    Original citation
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