CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: Werner helicase interacting protein isoform 1
    Symbol: WRNIP1
    Organism: Homo sapiens
    NCBI Accession: NP_064520
    SubstrateDB: 27239
    [Sequence on/off]
    MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAK
    RRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSG
    KRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHP
    RALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHI
    IASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTI
    TLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEP
    AMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHI
    LYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVA
    AYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPPVPLHLRNAPTRLMKDLG
    YGKGYKYNPMYSEPVDQEYLPEELRGVDFFKQRRC
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: MRPD-TLQD
    Position: 234-235
    Protease
    Definition: granzyme B (Homo sapiens-type)
    Organism: Homo sapiens
    MEROPS ID: MER000168
    PMAP ID: pmap.17497
    MEROPS code: S01.010
    Consequence
    Unknown
    Pathway
    Apoptosis
    Disease
    Viral infection, Cancer
    Method_of_ID
    Mass spectrometry
    Original citation
    Comments and others