CutDB: a proteolytic event database
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  • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: BCL2/adenovirus E1B 19kD interacting protein 2
    Symbol: BNIP2
    Organism: Homo sapiens
    NCBI Accession: NP_004321
    SubstrateDB: 27243
    [Sequence on/off]
    MLCGFQEDATPPPPPRPRRLHRRLPRPEEVGMLSLPPGLLTVSGSAAAADAVPLRPGDWAGVSTADRGER
    APLGPAFCDLAVSPTSPAWRGEEDEGAKASSGDIGSLDYQEFVVDIESRLRMEGVELKEEWQDEDFPIPL
    PEDDSIEADILAITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPS
    ENSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGY
    YGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKC
    YQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQV
    DQELNGKQDEPKNEQ
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: IEAD-ILAI
    Position: 149-150
    Protease
    Definition: granzyme B (Homo sapiens-type)
    Organism: Homo sapiens
    MEROPS ID: MER000168
    PMAP ID: pmap.17497
    MEROPS code: S01.010
    Consequence
    Unknown
    Pathway
    Apoptosis
    Disease
    Viral infection, Cancer
    Method_of_ID
    Mass spectrometry
    Original citation
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