CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: lamin A/C isoform 2
    Symbol: LMNA
    Organism: Homo sapiens
    NCBI Accession: NP_005563
    SubstrateDB: 3360
    UniProt Accession: Q5TCJ3
    [Sequence on/off]
    METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVV
    SREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEAL
    LNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNI
    YSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAER
    NSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRA
    RMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
    LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLK
    AGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDD
    LLHHHHVSGSRR
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: VEID-NGKQ
    Position: 230-231
    Protease
    Definition: caspase-1
    Organism: Homo sapiens
    NCBI GI: 15431328
    MEROPS ID: MER000850
    PMAP ID: pmap.22029
    MEROPS code: C14.001
    Method_of_ID
    Mutagenesis
    Original citation
    Acknowledgment
    HPRD_mod
    Comments and others