CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: Caspase 1 isoform alpha precursor
    Symbol: CASP1
    Organism: Homo sapiens
    NCBI Accession: NP_150634
    SubstrateDB: 3368
    UniProt Accession: P29466
    [Sequence on/off]
    MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQ
    ICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEE
    AQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASD
    MTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVI
    IIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFI
    GRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: WFKD-SVGV
    Position: 297-298
    Protease
    Definition: caspase-1
    Organism: Homo sapiens
    NCBI GI: 15431328
    MEROPS ID: MER000850
    PMAP ID: pmap.22029
    MEROPS code: C14.001
    Original citation
    Acknowledgment
    HPRD
    Comments and others