CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: Coagulation factor XII precursor
    Symbol: F12
    Organism: Homo sapiens
    NCBI Accession: NP_000496
    SubstrateDB: 3653
    UniProt Accession: P00748
    [Sequence on/off]
    MRALLLLGFLLVSLESTLSIPPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHKCTHKGRPGPQ
    PWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPHCLCPQHLTGNHCQKEKCFEPQL
    LRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRTNPCLHGGRCLEVEGHRLCHCPVGYTGPFCD
    VDTKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNPDNDIRPWCFVL
    NRDRLSWEYCDLAQCQTPTQAAPPTPVSPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPS
    LTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAP
    EDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSG
    AARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQ
    GDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHTVS
    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: VVGG-LVAL
    Position: 376-377
    Protease
    Definition: matrix metallopeptidase-13
    Organism: Homo sapiens
    NCBI GI: 4505209
    MEROPS ID: MER001411
    PMAP ID: pmap.44672
    MEROPS code: M10.013
    Method_of_ID
    N-terminal sequencing
    Original citation
    Acknowledgment
    HPRD
    Comments and others