CutDB: a proteolytic event database
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    • This_entry_is_based_on_an_experiment.
    Substrate
    Definition: Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kda
    Symbol: EIF2S1
    Organism: Homo sapiens
    NCBI Accession: NP_004085
    SubstrateDB: 3916
    UniProt Accession: P05198
    [Sequence on/off]
    MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNEC
    VVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDD
    KYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKE
    ALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTD
    TDETELARQMERLERENAEVDGDDDAEEMEAKAED

    ....:....1....:....2....:....3....:....4....:....5....:....6....:....7
    Cut-site
    Sequence: AEVD-GDDD
    Position: 301-302
    Protease
    Definition: caspase-6
    Organism: Homo sapiens
    NCBI GI: 14916483
    MEROPS ID: MER002708
    PMAP ID: pmap.26722
    MEROPS code: C14.005
    Original citation
    Acknowledgment
    HPRD
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